Introduction: Rubinstein-Taybi syndrome (RSTS) is a rare congenital disorder characterized by developmental and intellectual disability, broadening of thumbs and halluces, and characteristic facial features.Pathogenic variants in CREBBP lead to RSTS type 1 (RSTS1) and in EP300 lead to RSTS type 2 (RSTS2).Individuals with RSTS can demonstrate a vari
Despite global economic fluctuations, the travel and tourism industry are gradually expanding.However, the pandemic has created many obstacles for the tourism industry.Due to COVID -19, although there is still Blushes a strong desire to travel, demand is low as most domestic travellers are more cautious in their travel intentions.However, social me
Approximately one third of individuals with major depressive disorder (MDD) do not respond to antidepressant treatments; but what does treatment-resistant depression (TRD) mean? With this article, I aim Support Socks to provide an overview of the clinical and operational criteria currently used to define TRD, highlighting core gaps in knowledge and
Abstract Extracellular matrix (ECM) deposition after central nervous system (CNS) injury leads to inhibitory scarring in humans and other mammals, whereas it facilitates axon regeneration in the zebrafish.However, the molecular basis of these different fates is not understood.Here, we identify small leucine-rich proteoglycans Blushes (SLRPs) as a c