BEHAVIORAL AND NEUROPSYCHIATRIC CHALLENGES ACROSS THE LIFESPAN IN INDIVIDUALS WITH RUBINSTEIN-TAYBI SYNDROME



Lost in translation. The quest for definitions of treatment-resistant depression with a focus on inflammation-related gene expression

Approximately one third of individuals with major depressive disorder (MDD) do not respond to antidepressant treatments; but what does treatment-resistant depression (TRD) mean? With this article, I aim Support Socks to provide an overview of the clinical and operational criteria currently used to define TRD, highlighting core gaps in knowledge and

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Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Abstract Extracellular matrix (ECM) deposition after central nervous system (CNS) injury leads to inhibitory scarring in humans and other mammals, whereas it facilitates axon regeneration in the zebrafish.However, the molecular basis of these different fates is not understood.Here, we identify small leucine-rich proteoglycans Blushes (SLRPs) as a c

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